Ntshediseng holds a BCom in Accounting from the University of the Witwatersrand and an MBA from the Gordon Institute of Business Science. She began her career in the banking arena as a consultant at Investec Private Bank after which she joined Business Partners Limited in 2008 as a Business Analyst. She subsequently joined the National Empowerment Fund as a Dealmaker and later promoted to Senior Associate in the Wholesale Facility division within the iMbewu fund.
She joined Sanlam Private Equity as an Investment Associate in March 2013. Her responsibilities include the origination, negotiation, structuring and execution of new investments as well as the monitoring and exit of existing portfolio assets. She represents SPE as a non-executive director on the boards of the portfolio companies for which she is responsible.